Effectiveness of Bilateral Repetitive Transcranial Magnetic Stimulation on Anhedonia and Depression Symptoms in Major Depressive Disorder Patients

Document Type : Original Article

Authors

1 Department of psychology, Faculty of Literature and Human Science, Khoram Abad, Iran

2 Department of Psychology, Faculty of Literature and Human Sciences, Lorestan University, Khoramabad, Lorestan, Iran

Abstract

Introduction: The aim of this study was to investigate the effectiveness of a bilateral repetitive transcranial magnetic stimulation (rTMS) on anhedonia among patients with MDD.
Method: In a randomized controlled trial study with pre-post test design and control group among referred MDD patients to Atieh Clinical Neuroscience Center, a total sample of 58 patients were selected and were randomized into two experimental and control groups. The experimental group patients were received 10 sessions of a 10-Hz rTMS on the left dorsolateral prefrontal cortex (DLPFC) and a 1-Hz rTMS on the right DLPFC. Control group received a sham rTMS. The Snaith-Hamilton Pleasure Scale (SHAPS) and the Hamilton Depression Rating Scale (HDRS)) were used to evaluation participants both before and after treatment.
Results: Results of a Multivariate Analysis of Covariance showed that a bilateral rTMS significantly decreased the mean scores for anhedonia and depression symptoms in the experimental group than control.
Conclusion: This study indicated that rTMS could be considered as an effective approach in the treatment of anhedonia and depression symptoms of the MDD patients.

Keywords

Main Subjects

References

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History

  • Receive Date: 30 April 2018
  • Accept Date: 31 October 2018

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