اثربخشی تحریک الکتریکی فراجمجمه‌ای بر بازداری کودکان مبتلا به صرع کانونی مقاوم به درمان دارویی

نوع مقاله: مقاله پژوهشی

نویسندگان

1 کارشناس ارشد روانشناسی عمومی دانشگاه فردوسی مشهد، مشهد، ایران

2 دانشیار، گروه علوم تربیتی هسته پژوهشی علوم شناختی دانشگاه فردوسی مشهد، مشهد، ایران

3 استادیار، گروه روانشناسی دانشگاه فردوسی مشهد، مشهد، ایران

4 استاد، فوق تخصص اعصاب کودکان دانشگاه علوم پزشکی مشهد، مشهد، ایران

5 فلوشیپ فوق تخصصی اعصاب اطفال دانشجوی دانشگاه علوم پزشکی مشهد، مشهد، ایران

چکیده

مقدمه: صرع بیماری مزمنی است که علائم بالینی آن ایجاد تشنجات صرعی است که با حملات ناگهانی و معمولاً بدون عامل برانگیزنده، اختلال هشیاری و حرکات غیر ارادی مشخص می‌شود. هدف پژوهش حاضر بررسی اثربخشی تحریک الکتریکی فراجمجمه‌ای (tDCS) بر بازداری کودکان مبتلا به صرع کانونی پیچیده‌ی گیجگاهی مقاوم به درمان بود.




روش: طرح پژوهش حاضر  به صورت تک آزمودنی بود. جامعه پژوهش مراجعه‌کنندگان به کلینیک بیمارستان قائم مشهد در سال 1394 تا 1396 بودند که توسط پزشک متخصص داخلی اعصاب به صرع کانونی مقاوم به درمان دارویی تشخیص داده شدند. سن مورد نظر افراد نمونه بین 7 تا 11 سال است و تعداد 5 نفر انتخاب شدند. ابزار پژوهش شامل آزمون هوش مازهای پروتئوس و آزمون برو – نرو بودند. نتایج با استفاده از تحلیل دیداری نمودار و درصد بهبودی تحلیل شدند.




یافته‌ها: نتایج نشان داد که در آزمون برو – نرو نمرات آزمودنی‌ها در خطای ارتکاب سیر نزولی داشته است. سه آزمودنی  درصد بهبودی بالای 50 داشتند که نشان‌دهنده‌ی بهبودی و معناداری بالینی در بازداری است. خطای ارتکاب دو آزمودنی دیگر نیز  کاهش پیدا کرده بود و بهبودی اندکی گزارش کردند.




نتیجه‌گیری: پژوهش حاضر نشان داد که مداخله tDCS می‌تواند نقش بسزایی در بهبود بازداری کودکان مصروع داشته باشد. بنابراین استفاده از شیوه‌های نوین درمانی مانند tDCS که نیازمند دارو نیست اثرات مفیدی در وضعیت زندگی این افراد و بهبود عملکردهای روانی آن‌ها خواهد داشت.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Effectiveness of Transcranial Direct Current Stimulation on improving the inhibition in childhood drug-resistant temporal lobe Epilepsy

نویسندگان [English]

  • H Yavarzadeh, 1
  • A Ghanaee-Chamanabad, 2
  • M.J Asghari Ebrahim-Abad, 3
  • F Ashrafzadeh, 4
  • N. Hashemi, 5
1 Department of Psychology Faculty of Education and Psychology, Ferdowsi university of mashhhad, Mashhad, Iran
2 Department of Education Faculty of Education and Psychology, ferdowsi university of mashhad, mashhad, iran
3 Department of Psychology Faculty of Education and Psychology, Ferdowsi university of mashhhad, Mashhad, Iran
4 MD, Pediatric neurologist, Professor of Mashhad University of Medical science, Iran.
5 MD, Pediatric Neurology fellowship, Mashhad University of Medical science, Iran.
چکیده [English]

Introduction: Epilepsy is a chronic disease characterized by epileptic seizures that are identified by suddenly attacks, usually without eliciting external event, along with disorder of consciousness and involuntary movements. The purpose of the present study was to examine the effect of transcranial direct current stimulation (tDCS) on improving the inhibition of childhood drug-resistant temporal lobe Epilepsy.




Method: The present research use a single subject design. The research population included all clients referred to the clinic of Ghaem Hospital of Mashhad, in 2015 to 2018 and were diagnosed by an expert neurologist with experience on drug-resistant temporal lobe Epilepsy. The age range of subjects were between 6 and 18 years old and 5 patients were selected. The research tools were Porteus Maze Test and the Go-No Go Test. The final results were analyzed using a visual analysis chart and a  recovery percentage formula.




Results: Results were shown that in the Go-No Go Test, for the majority of subjects the commission error decreased. The percentage of recovery for 3 subjects were over 50 percent which is a sign of clinical recovery. The other two subjects revealed a lower recovery in commission error.




Conclusion: This study suggest that tDCS intervention  play a significant role on improving the inhibition of epileptic children. Hence the use of such a new therapies as tDCS that requires no medication will have beneficial effects on patients’ lives and their mental functioning.

کلیدواژه‌ها [English]

  • Inhibition
  • childhood epilepsy
  • drug-resistant
  • temporal lobe epilepsy
  • transcranial direct current stimulation
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